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Old January 21st, 2015, 04:10 PM   #121
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Nanobot micromotors deliver medical payload in living creature for the first time



Researchers working at the University of California, San Diego have claimed a world first in proving that artificial, microscopic machines can travel inside a living creature and deliver their medicinal load without any detrimental effects. Using micro-motor powered nanobots propelled by gas bubbles made from a reaction with the contents of the stomach in which they were deposited, these miniature machines have been successfully deployed in the body of a live mouse.

The picayune robots used in the research were tubular, about 20 micrometers long, 5 micrometers in diameter, and coated in zinc. Once the mouse ingested these tiny tubes and they reached the stomach, the zinc reacted with the hydrochloric acid in the digestive juices to produce bubbles of hydrogen which then propelled the nanobots along like miniature rockets.

Reaching speeds of up to 60 micrometers per second, the nanobots headed outwards toward the stomach lining where they then embedded themselves, dissolved, and delivered a nanoparticle compound directly into the gut tissue.

According to the researchers, of all the nanobots deployed in the stomach of the mouse, those that reached the stomach walls remained attached to the lining for a full 12 hours after ingestion, thereby proving their effectiveness and robust nature.

SOURCE: http://www.gizmag.com/nanobot-microm...reature/35700/
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Old January 27th, 2015, 04:32 AM   #122
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Oxytocin for Autism?

Scientists find that the hormone improves sociability in a mouse model of autism.

By Ruth Williams | January 21, 2015
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Old February 1st, 2015, 03:31 AM   #123
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New Research Reveals the Real Causes of Depression
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Old February 1st, 2015, 03:43 AM   #124
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Fertility Treatment Fallout

Mouse offspring conceived by in vitro fertilization are metabolically different from naturally conceived mice.

By Jyoti Madhusoodanan | January 1, 2015
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Old February 4th, 2015, 01:40 AM   #125
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UK's parliament takes unprecedented step and allows human genome manipulation to prevent mitochondrial diseases

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Old February 4th, 2015, 04:18 AM   #126
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Injectable 3D cell factories to fight cancer in the body

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Old February 6th, 2015, 06:41 PM   #127
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Robot Scientist Discovers Potential Malaria Drug
The machine called Eve is packed with innovations for finding drugs faster
February 5, 2015 |By Andy Extance
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Old February 6th, 2015, 06:43 PM   #128
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Carnivorous mushroom provides immune system clues

Friday, 6 February 2015 Anna Salleh
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Old February 9th, 2015, 11:38 PM   #129
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Old February 9th, 2015, 11:39 PM   #130
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Old February 18th, 2015, 03:33 PM   #131
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Childhood trauma isn’t something you just get over as you grow up. Pediatrician Nadine Burke Harris explains that the repeated stress of abuse, neglect and parents struggling with mental health or substance abuse issues has real, tangible effects on the development of the brain. This unfolds across a lifetime, to the point where those who’ve experienced high levels of trauma are at triple the risk for heart disease and lung cancer. An impassioned plea for pediatric medicine to confront the prevention and treatment of trauma, head-on.
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Old February 21st, 2015, 06:20 PM   #132
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EU approves Western world's first stem-cell therapy

Europe has approved the Western world's first medicine containing stem cells to treat a rare condition caused by burns to the eye, marking a milestone in the use of the technology.

Holoclar, from privately held Italian company Chiesi, was given a marketing green light on Friday by the European Commission for treating so-called limbal stem cell deficiency due to physical or chemical burns. Left untreated, the condition can result in blindness.

The therapy is manufactured by Holostem Advanced Therapies, a spin-off of the University of Modena and Reggio Emilia. The latter’s co-founder Graziella Pellegrini explained that Holoclar is a graft of epithelium taken from the patient that looks like a contact lens which is then transplanted, allowing them to obtain a long-term transparent cornea and full recovery of visual acuity, without any rejection concerns.

The conditional marketing authorization had been expected, following a positive recommendation by the European Medicines Agency in December.

Chiesi said the approval meant that Holoclar would be available "in the near future" to all suitable patients in Europe, including people who have suffered eye injuries caused by solvents, acids, abrasive and chemical agents".

reuters - pharmatimes
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Old February 24th, 2015, 05:36 AM   #133
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Stem cell breakthrough may allow same gender couples to create babies



Researchers from Cambridge University and Israel’s Weizmann Institute of Science are claiming a stem cell research breakthrough that would allow a baby to be created from the skin cells from two adults, no matter their gender. This potentially allows for infertile couples to have their own children without resorting to sperm or egg donors, and may provide the means for same sex couples to produce their own babies.

Previously only successful in experiments on mice, the new research has been conducted on human cells for the first time. In this study, the researchers paired stem cell lines from embryos with the skin of a range of different adults, with the resultant cells compared to aborted fetuses to determine an identical match.

Techniques devised to create same-sex offspring are not new. Some experiments involve the manipulation of fibroblasts in mice resulting in offspring with the genetic traits of multiple male mice, whilst others have used bone marrow stem cells extracted from males to trigger spermatogonia.

However, in this latest research, stem cells and adult human skin have been combined for the first time to create an entire new germ-cell line (that is, cells that will become embryos). Derived from ten different donor sources, the new germ-cell lines were created from 10 different donor sources – five embryos and five adults.

Intrinsic to this pairing was the SOX17 gene. A master gene, SOX17 usually works to direct stem cells to be “programmed” to become whatever organs or body parts are required – in other research this techniques has been used to create lung, gut, and pancreas cells.

The manipulation of the gene to be part of a primordial germ cell specification (that is, direct it to create cells that will become an entire human), however, is a new development pioneered by the team and has allowed them to follow this discovery with actually making primordial germ cells in the lab. This stage in a baby’s development is known as "specification", and once primordial germ cells become specified, they continue to develop inexorably toward precursor sperm or ova cells.

Creating human egg and sperm cells from the skin of two adults of the same gender immediately raises the possibility of same sex couples procreating and offering an alternate pregnancy path for infertile couples. Of course, it also opens the door to a new minefield of ethical and moral implications, but the researchers note that many people may potentially benefit from the technique.

SOURCE: http://www.gizmag.com/stem-cell-skin...embryos/36221/
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Old February 24th, 2015, 06:01 AM   #134
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Wow, that could be huge if they perfect the method and ever look for government approval.
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Old February 24th, 2015, 10:27 PM   #135
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The Three-Parent Baby's First Step

Read more: http://www.nytimes.com/2015/02/23/op...step.html?_r=0

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LONDON — The British Parliament can be an archaic, backward-looking institution, wedded to tradition, and not known for taking a revolutionary stance. Yet its members have just made a groundbreaking decision, one that no other legislature has so far been willing to contemplate.

They approved legislation that makes Britain the first country to allow the creation of what many call “three-parent babies.” Supporters say the procedure will enable women to avoid passing on certain severe and even deadly genetically inherited diseases. But many regard the new law as an unwise, even immoral, move — the first step toward the creation of “designer babies.” Some even see it as a new experiment in eugenics.

“Three-parent babies” is a sensationalized term to describe a special form of in vitro fertilization, or I.V.F., that is better labeled “mitochondrial transfer.”
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Old March 6th, 2015, 01:43 PM   #136
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Lung cancer stem cell therapy to be trialled in UK

Friday 6 March 2015 07.53 GMT

British patients will be the first in the world to receive a pioneering cell therapy that scientists hope will transform the treatment of lung cancer.

The treatment uses stem cells taken from bone marrow that have been genetically modified to find and destroy cancer cells.

If successful, the treatment would offer hope to lung cancer patients, who continue to face one of the worst outlooks of all cancer patients. More than 40,000 people are diagnosed with the disease in the UK each year and only 5% of patients survive beyond 10 years.

http://www.theguardian.com/society/2...erapy-trial-uk


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Old March 6th, 2015, 02:54 PM   #137
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the one disease I'm quite afraid of (namely, Ich bin ein smoker)
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Old March 7th, 2015, 09:44 AM   #138
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If only you could do something about it.
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Old March 7th, 2015, 02:52 PM   #139
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April, 23rd 2013. Last time I had a cigarette. Best decision in my life.
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Old March 8th, 2015, 12:05 AM   #140
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